Gastric polyps found at upper gastrointestinal endoscopy and its relation with proton pump inhibitor intake: A single-centre study

Abstract

Background: This cross-sectional study was designed to see the frequency and associated factors of gastric polyps among patients undergoing endoscopic examination of the upper gastrointestinal tract. Methods: Consecutive patients who underwent endoscopic examination of upper GIT were included. Epidemiologic information, indication, history of proton pump inhibitor intake with duration, and endoscopic findings were recorded in a standard data sheet. SPSS version 20 was used for statistical analysis. Percentage, mean and SD were calculated for continuous data and the chi-square test was applied to see the relation of polyps with age, sex, duration, regularity, and dose of PPI use. Results: A total of 432 patients (Mean age 42.99±15.53) were included in this study. Of them, 198 (45.8%), 233 (53.93%), and 01 (0.23%) respectively were male, female, and third gender. 427 (98.9%) patients were taking PPI. A total of 109 (25.23%) patients had single or more polyps. of them, 90 (82.56%) patients had polyps limited within cardia and or fundus. Polyps were found more common among patients of age above 45 years (69; 63.30%), and females (70; 64.22%). The detection rate of gastric polyps increases with the duration of PPI intake of more than one year (102; 93.58%), regular intake (69; 63.30%), and twice daily doses (93; 85.32%) of PPI intake. Conclusions: Gastric polyps especially at fundus and cardia are common. Age, female sex, prolonged period, and regular and twice daily intake of PPI are found to be associated factors of gastric polyps.