CT Guided Fine Needle Aspiration Cytology and Radiologic Correlation in Diagnosing Lung Neoplasms

Abstract

Background: Lung cancer represents the leading cause of cancer incidence and mortality among men globally, while for women, it ranks as the third most prevalent cause of cancer incidence and the second leading cause of cancer-related deaths. This study aimed to assess the performance of CT-guided fine needle aspiration cytology (FNAC) and radiology and their correlation in diagnosing lung carcinoma. CT guided biopsy was considered as gold standard. Methods: This cross-sectional observational study was conducted at the Department of Pathology in Jalalabad Ragib-Rabeya Medical College and Hospital, from January 2023 to December 2023 on 60 patients having suspected lung mass were purposively selected as study subjects.  Result: Cytology has a sensitivity of 93.48% and a specificity of 50.00%, with a positive predictive value (PPV) of 86.00% and a negative predictive value (NPV) of 70.00%. Radiology shows a sensitivity of 89.13% and a specificity of 50.00%, with a PPV of 85.42% and an NPV of 58.33%. Conclusion: This study concludes that, while both cytology and radiology contribute valuable information in diagnosing cancerous lesions, their combined use may enhance diagnostic accuracy, with each test offering unique strengths. This underscores the importance of integrating multiple diagnostic modalities to optimize patient care and management.