Correlation of Serum Uric Acid and Troponin I Level in Patients with Acute Myocardial Infarction

Background: Acute myocardial infarction (AMI) is a significant contributor to global mortality, with ischemic heart disease being the predominant form. Risk factors for cardiovascular disease have been linked to elevated serum uric acid levels. This study investigates the relationship between AMI patients serum uric acid and troponin I levels. Objective: The study sought to determine the correlation between serum uric acid and troponin I levels in patients with AMI and to evaluate the difference in uric acid levels between different types of AMI. Methods: A cross-sectional comparative study was conducted at Dhaka Medical College over one year, involving 100 AMI patients aged 30 to 70. Serum uric acid and troponin I levels were measured, and demographic data, including age, gender, BMI, smoking status, and hypertension, were recorded. Statistical analyses were performed using SPSS software. Results: The mean serum uric acid level was significantly higher in AMI patients (6.03 ± 1.68 mg/dl) compared to healthy individuals (4.65 ± 1.19 mg/dl), with a positive correlation between uric acid and troponin I levels (r=0.621, p < 0.001). Additionally, serum uric acid levels were significantly higher in ST-segment elevated MI (STEMI) patients (7.45 ± 0.81 mg/dl) compared to non-STEMI patients (4.61 ± 0.96 mg/dl). Conclusions: Hyperuricemia appears to be a potential risk factor for AMI development. Regular screening of serum uric acid levels may aid in prognostic assessment and cardiovascular risk management. The results highlight the need for prompt action to detect and treat AMI in its early stages.