Proportion of cervical intraepithelial neoplasia in patients with persistent inflammatory Paps smear

Background: Among the chronic diseases, cervical cancer is still a public health problem. An inflammatory Pap smear may miss cervical precancerous changes due to low sensitivity and high false negativity of Pap smear. Methods: This was a cross-sectional type of descriptive study on 384 married non-pregnant patients aged ≥ 18 years presented with persistent inflammatory changes on Pap smear attending in the OPD of Obstetrics and Gynecology, Rajshahi medical college Hospital, Rajshahi over a period of 1 year from June 2020 to July 2021. Pre-designed, validated, semi-structured questionnaire and purposive sampling technique were used to gather information from the patients. Results: According to colposcopic grading, 46.60% of the women harbor CIN-1, 10.70% CIN-2, 2.60% CIN-3 and remaining 40.10% chronic cervicitis among the women with persistent inflammatory changes on Pap smear. Again, according to histological grading, 26.60% of the women had CIN-1, 4.70% CIN-2 and remaining 68.80% chronic cervicitis. Conclusions: Colposcopy is an excellent tool for evaluation of cervical carcinoma if operator is properly trained. Concomitant histology also increases the sensitivity and specificity of the test.